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KMID : 0613820050150060968
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Journal of Life Science
2005 Volume.15 No. 6 p.968 ~ p.971
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Investigation of Porcine Melanocortin-4 Receptor (MC4R) Polymorphism on Economic Traits
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Kim Kwan-Suk
Shin Hee-Young
Lee Jung-Jae
Hong Sung-Kwang
Choi Bong-Hwan
Kim Tae-Hun
Lee Hak-Kyo
Cho Byung-Wook
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Abstract
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The Melanocortin-4 receptor gene (MC4R) regulates the energy balance and the genetic basis of obesity. A polymorphism in the porcine melanocortin-4 receptor has previously shown to be associated with growth, fat deposition and feed intake. In this study, the polymorphism of the gene was studied in several pig breeds of Duroc, Landrace, Berkshire, and Yorkshire. The results showed that the frequencies of MC4R genotype varied among those breeds. Association analyses were also performed between the MC4R polymorphism and average daily gain, feed conversion ratio, backfat thickness and lean percentage phenotypes. The results strongly support that the MC4R polymorphism can be used DNA marker selection indicator for economically important traits for pig breeding program in Korea.
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